State Republican Chairman Ed Cox in an interview Monday said Gov. Andrew Cuomo’s efforts to help Democrats retake control of the state Senate is being fueled by national ambitions.

In particular, Cox said Cuomo is being influenced in part by the populist wing of the party as personified by Massachusetts Sen. Elizabeth Warren and New York City Mayor Bill de Blasio.

“This is really being driven by national politics,” Cox said. “Andrew Cuomo has national ambitions. The national party is going hard left as evidenced by Elizabeth Warren and other candidates like her. Andrew Cuomo because of national ambitions is going that way and is taking the New York Democratic Party, driven by Mayor de Blasio, in that direction.”

Cuomo, along with a coalition of labor groups, the Working Families Party and de Blasio are actively supportive of a full Democratic takeover of the Senate.

The governor, along with the mayor, helped negotiate the plan to have the five-member Independent Democratic Conference form a new coalition with mainline Democrats in the chamber after Election Day.

The IDC currently is aligned with Senate Republicans, who were able to retain majority control of the Senate thanks to the arrangement.

The negotiations for the IDC to break its current alliance had been going on for weeks, but Cox said Senate GOP Leader Dean Skelos wasn’t to blame for the coalition blowing up.

“I don’t think Dean Skelos could have seen this coming,” Cox said.

Republicans now plan to tie Cuomo to de Blasio as an effort to woo moderate voters to both their Senate candidates as well as their gubernatorial candidate, Westchester County Executive Rob Astorino.

“I think there are a lot of sensible Democratic voters in the suburbs, on Long Island and upstate that realize the last time Democrats controlled everything in Albany they increased taxes by $14 billion, left a $10 billion deficit,” Cox said. “It’s time for the Republicans to have the governorship as well as the state Senate.”

Still, Cuomo has governed as a non-partisan, embracing Senate Republicans on key issues, who have in turn helped pass his legislative victories, such as same-sex marriage and the SAFE Act gun control law.

Cuomo has played up his credentials in recent weeks as someone who can work across the aisle, but Cox said this agreement tarnishes that reputation.

“This is definitely going to drive a lot of moderate and conservative Democrats to come out and vote for our Republican candidates,” he said. “They know what the threat this is to New York state.”