Critics of Gov. Andrew Cuomo — including his Republican gubernatorial opponents and a GOP-aligned super PAC — pounce on the news Tuesday of the guilty verdict in the corruption case of his close former aide.

The all have some stake in seeing Cuomo be weakened politically as a result of the trial’s outcome and the outcomes of the future trials to come this year. But Cuomo himself has largely stayed silent on the trial as it unfolded, saying he has not wanted to impact the judicial process.

Cuomo was not accused of any wrongdoing, but the trial also raised questions — left unanswered by Cuomo himself — as how his office was run while Percoco seemingly had free reign.

“With or without the conviction, this is a pretty good indication that we need a change at the top,” said Sen. John DeFrancisco, one of the Republican gubernatorial candidates. “Also, we need changes in the laws as well.”

DeFrancsico added: “You know he should be able to explain fully what Percoco was doing in the governor’s office. And more importantly, there should be an investigation.”

Chief among the questions raised by the trial was Percoco’s appearances in Cuomo’s office in 2014 while he was ostensibly running the governor’s re-election campaign and not on the government payroll.

Dutchess County Executive Marc Molinaro, who is also seeking the GOP nomination, said Cuomo should submit himself to some questioning.

“Our government is of the people and New Yorkers need and deserve an honest government working for them, working in their best interest,” Molinaro said.

“Finally, while the verdict is in, the trial raises as many disturbing questions as were answered and the Governor should subject his administration to an independent investigation by the Attorney General. Otherwise, the Attorney General should immediately begin one.”

Former New Jersey Gov. Chris Christie faced a barrage of questions after his former aides were accused of shutting down lanes of the George Washington Bridge out of political retaliation. Christie answered the questions, but saw his popularity plummet and his presidential campaign never got off the ground.

The trial also raised questions about the structure of Albany and what some good-government advocates see as a culture of corruption at the Capitol.

“There’s too much power in too few hands,” said Assembly Minority Leader Brian Kolb. “When you’re talking about budget negotiations, you don’t have every legislative leader in the room talking about the largest piece of cash that you dole out every year. There’s no turn over, there’s no change over.”

Democratic Assembly Speaker Carl Heastie was less confident legislative changes will be made in the wake of the trial. Good-government reformers have called for strengthened transparency measures when it comes to contracting and other economic development spending.

“There seems to always be a thirst for a new bill when something like this happens,” Heastie said. “But from the verdict that came back, those are clearly already against the law. I don’t know what’s the legislative remedy for something that a jury has decided is against the law.”

Heastie called any corruption news tough for Albany, but said the broad brush should not be applied to all public officials.

“These events always are tough,” he said. “When there’s a verdict that says there’s a violation of the public trust, it’s a tough day. I still maintain that the overwhelming number of people who take on public service do the right thing.”