Senate Republicans on Wednesday signaled their one-house budget resolution next week will not include an estimated $800 million in taxes and surcharges included in Gov. Andrew Cuomo’s $152 billion budget proposal — including the extension of the millionaires tax, which Cuomo has insisted is key to his spending plan.

The surcharges and tax hikes include motor vehicles fees, Internet sales tax revenue and pre-paid cellphones.

And the conference will reject Cuomo’s proposal to extend a higher tax rate on those who make more than $1 million. Extending tax, due to expire at the end of the year, is backed by Sen. Jeff Klein, the Bronx Democrat who chairs the Independent Democratic Conference.

“Middle-class taxpayers are struggling under the crushing weight of property taxes, income taxes, mortgages and the skyrocketing costs of higher education for their children,” said Majority Leader John Flanagan. “In this environment, these new taxes and fees are the last thing hardworking families want or need. We must make it more affordable to live and work in New York, not less, and that’s exactly what our Senate budget will reflect.”

Cuomo has insisted the tax extension is necessary in order to generate revenue for a middle-class tax reduction set to take effect in the coming fiscal year, which begins April 1.

Assembly Democrats are expected to propose a separate one-house budget resolution that includes increasing taxes for those who make $5 million and more, beyond the straight extension.

Still, Senate Republicans have signaled the extension is the equivalent to a tax increase.

“Our overburdened taxpayers need and deserve relief, and the Senate is rejecting these additional taxes because we are committed to enacting a fiscally responsible budget,” said Sen. Cathy Young, the Finance Committee chairwoman. “We need to make our state a more affordable place to live, work and grow jobs, so that everyone has the opportunity to succeed.”

Senate Republicans last backed an extension of the millionaires tax in 2011 when Cuomo and lawmakers agreed to changes in the tax rates in a year-end special session of the Legislature.

At a cabinet meeting last week, Cuomo called the millionaires tax a “seminal” issue in the budget.

“If you do not extend the millionaires tax, you have a tremendous hole in the budget,” Cuomo said, “and I don’t know how you complete a budget without the millionaires tax.”